Fmoc-D-Aspartic Acid Alpha-T-Butyl Ester
Fmoc-D-Asp-OTBU
CAS: 134098-70-7
Molecular Formula: C23H25NO6
Fmoc-D-Aspartic Acid Alpha-T-Butyl Ester - Names and Identifiers
Fmoc-D-Aspartic Acid Alpha-T-Butyl Ester - Physico-chemical Properties
| Molecular Formula | C23H25NO6 |
| Molar Mass | 411.45 |
| Density | 1.251±0.06 g/cm3(Predicted) |
| Melting Point | 90-98°C |
| Boling Point | 617.4±55.0 °C(Predicted) |
| Flash Point | 327.2°C |
| Solubility | Soluble in DMF. |
| Vapor Presure | 4.21E-16mmHg at 25°C |
| pKa | 4.08±0.19(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | 1.576 |
| Physical and Chemical Properties | Storage Conditions: Store at RT. |
Fmoc-D-Aspartic Acid Alpha-T-Butyl Ester - Risk and Safety
| HS Code | 29224999 |
| Hazard Class | IRRITANT |
Fmoc-D-Aspartic Acid Alpha-T-Butyl Ester - Introduction
Fmoc-D-aspartic acid -1-tert-butyl ester is an amino acid protecting group, which is widely used in chemical synthesis. The following is a description of its nature, use, preparation and safety information:
Nature:
Fmoc-D-Aspartic acid -1-tert-butyl ester is a light yellow solid, soluble in organic solvents such as dimethyl sulfoxide (DMSO) at room temperature, and has strong photosensitivity. Its molecular formula is C25H27NO6 and its relative molecular mass is 433.48g/mol.
Use:
Fmoc-D-aspartate -1-tert-butyl ester is mainly used in the synthesis of polypeptides and proteins as a protective group for amino acids. It can be used to synthesize the first amino acid of the polypeptide chain, as well as aspartic acid residues that need protection at other positions. In addition, it can also be used in the fields of peptide chemistry, drug research and protein engineering in solid phase synthesis.
Preparation Method:
The preparation of Fmoc-D-aspartic acid -1-tert-butyl ester usually uses a chemical synthesis method. Among them, the tert-butyl ester group is combined with aspartic acid to form Fmoc-D-aspartic acid -1-tert-butyl ester. This method requires the use of the corresponding reagents and solvents and the appropriate process conditions to carry out the reaction.
Safety Information:
Fmoc-D-Aspartic acid-l-tert-butyl ester is generally safe under proper handling and storage. However, it can be irritating to the eyes and skin, so appropriate personal protective equipment, such as lab gloves and glasses, should be worn during operation. In addition, it should be stored in a dry, cool place, and avoid prolonged exposure to light to reduce the impact of photosensitivity. Detailed safety information can be found in the Safety Data Sheet (SDS) of the relevant chemical.
Nature:
Fmoc-D-Aspartic acid -1-tert-butyl ester is a light yellow solid, soluble in organic solvents such as dimethyl sulfoxide (DMSO) at room temperature, and has strong photosensitivity. Its molecular formula is C25H27NO6 and its relative molecular mass is 433.48g/mol.
Use:
Fmoc-D-aspartate -1-tert-butyl ester is mainly used in the synthesis of polypeptides and proteins as a protective group for amino acids. It can be used to synthesize the first amino acid of the polypeptide chain, as well as aspartic acid residues that need protection at other positions. In addition, it can also be used in the fields of peptide chemistry, drug research and protein engineering in solid phase synthesis.
Preparation Method:
The preparation of Fmoc-D-aspartic acid -1-tert-butyl ester usually uses a chemical synthesis method. Among them, the tert-butyl ester group is combined with aspartic acid to form Fmoc-D-aspartic acid -1-tert-butyl ester. This method requires the use of the corresponding reagents and solvents and the appropriate process conditions to carry out the reaction.
Safety Information:
Fmoc-D-Aspartic acid-l-tert-butyl ester is generally safe under proper handling and storage. However, it can be irritating to the eyes and skin, so appropriate personal protective equipment, such as lab gloves and glasses, should be worn during operation. In addition, it should be stored in a dry, cool place, and avoid prolonged exposure to light to reduce the impact of photosensitivity. Detailed safety information can be found in the Safety Data Sheet (SDS) of the relevant chemical.
Last Update：2024-04-09 20:52:54
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CAS: 134098-70-7
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CAS: 134098-70-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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